2024年Helix DNA评论

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脸颊拭子
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26 区域
  • 祖先血统
  • 健康与保健
由莫斯·斯特恩于2020年3月11日撰写
  • 祖先血统
  • 健康与保健

Helix Overview: Many Specialized Reports to Choose From

Helix Population Genomics employs exome sequencing as its DNA analysis method, delving deep into the protein-coding region of the genome. This comprehensive approach yields valuable insights into ancestry, potential health considerations, carrier status for genetic conditions, and physical traits. The critical question at hand is whether Helix’s utilization of exome sequencing results in more robust and informative reports. In this review, we will delve into the specifics to assess whether the additional testing costs are warranted.

How Helix DNA Works

Helix sends you a kit so that you can collect and send in a one-time saliva sample for DNA analysis. The kit contains everything you need to put your DNA “on-file” for future reports, such as the add-on ancestry report.

Helix Review

Note that you can only order Helix test kits in the United States.

Helix’s Ancestry Test

People take ancestry DNA tests to discover the ethnicities of their ancestors, where they lived, and how they migrated around the globe. Helix’s only test of this kind is called Helix Ancestry.

Helix Ancestry

Helix Review

This test explores your ancestors’ ethnic roots, broken down into 26 global regions within eight broad geographic regions: East Asia, Europe, Indigenous America, Arctic, Oceania, Middle East and North Africa, South Asia, and Sub-Saharan Africa. It tells you the percentages of these ethnicities reflected in your DNA.

The report can also tell you some interesting things based on your detected genetic traits. For example, you’ll learn whether you’re genetically adapted to high altitudes (mainly people of Tibetan descent) or to survival in the Arctic.

More practical value may be obtained from knowing if you’re likely to be lactose intolerant, better able to metabolize fat (like an Inuit), or resistant to malaria.

To get this free report, you first have to have taken one of the wellness tests (discussed next), so that Helix has your DNA on file.

How Helix Population Genomics Compares to Other Companies

When exploring genetic testing options, it’s helpful to compare different providers. The following table compares Helix Population Genomics with two of its major competitors, AncestryDNA and MyHeritage DNA. It highlights key features such as genetic testing options, ancestry analysis, health traits analysis, pricing, sample collection methods, processing time, privacy policies, and more.

Features Helix Population Genomics AncestryDNA MyHeritage DNA
Genetic Testing Yes Yes Yes
Ancestry Analysis Yes Yes Yes
Health Traits Analysis Yes No No
Carrier Status Testing No No No
Pharmacogenomics No No No
Raw Data Access Yes Yes Yes
Sample Collection Saliva or Cheek Swab Saliva Cheek Swab
Test Processing Time Varies (usually a few weeks) Varies (usually 6-8 weeks) Varies (usually 3-4 weeks)
Price Range $80 – $500 $99 – $149 $79 – $199
Privacy Policy Comprehensive privacy protections Comprehensive privacy protections Comprehensive privacy protections
Customer Support Available Available Available
Insurance Coverage Typically not covered Typically not covered Typically not covered

Pricing: Possibly Worth It

Helix accepts payments via Visa, MasterCard, American Express, and most other credit cards.

Most of Helix’s DNA tests are more expensive than similar ones from other companies, which could be because of its exome sequencing approach (rather than the more usual genotyping).

However, Helix does offer three tests for free, if you are already a Helix customer. After an initial purchase, you can also access most other tests at a discounted rate (sometimes at just 10% of the list price)!

Exome sequencing can identify the genetic variants in all of an individual’s genes, including very rare genetic variants that are only present in a small number of individuals. If this means it can pick up the gene variants for a rare Mendelian disease, it may well be worth paying the high price – at least for the first test.

祖先血统
kit
Ancestry
  • 结果分为26个区域组
  • 找出您是否有特定的适应能力,包括海拔和极地气候
  • 您可进行单独测试以确认您的尼安德特人血统

Customer Support: You Need to Be Specific

Helix’s self-support resources are provided in the form of a searchable Help Center populated with articles arranged into various categories. The accompanying chatbot always appears to be offline, but maybe I’ve just been unlucky.

Helix Review

If the self-support resources don’t answer your questions, you can call the company or fill out the “Contact Customer Support” form. I submitted an initial question to ask about whether the reports were worth the cost, and the support agent responded with a somewhat generic answer.

I asked a second question about the availability of tests internationally. This time, I received a more targeted response:

Helix Review

See Helix Deals

Higher Prices for Better Insights (and Some Free Stuff)

One of Helix’s key selling points is its use of exome sequencing rather than genotyping, which means that – theoretically – it could discover predispositions to rare genetic diseases that other companies’ DNA tests don’t detect. I can’t be sure that it does, and since I’m unlikely to be one of those rare cases, I’d personally prefer to take my chances with one of the other testing companies that cost less.

It is true to say that Helix goes into greater detail than most of its competitors in certain areas. For example, its CarrierCheck tests your carrier status for 67 different conditions. Likewise, the GenePrism: Actionable Insights report includes genetic risks for 32 diseases.

If you do decide to make the purchase, remember that getting your genome sequenced via one of Helix’s expensive tests also entitles you to free additional reports for Ancestry and Wellness (including one specifically for Women’s Wellness). Be sure to put these in your cart for better value-for-money.

See Helix Deals

FAQ

How accurate is Helix?

Helix is adequate in terms of accuracy. However, it can’t yet compare to some of the bigger names on the market, e.g., 23andMe and AncestryDNA. That’s in part due to its database size, which is comparably much smaller.

How long does it take to receive results from a Helix test?

Approximately 1-2 months.

How much does a Helix test cost? (Any discounts?)

Most of Helix’s DNA products are on the more expensive side of the pricing spectrum (US$144.99) than what you’d get from similar companies. That’s probably due to the testing methodology it uses (exome sequencing approach). On the bright side, however, Helix does offer three tests for free if you’re a customer already. After an initial purchase, you can also access most other tests at a discounted rate (sometimes at just 10% of the list price).

Who should consider taking a Helix test?

Given that Helix uses exome genome sequencing, which (in theory) can discover predispositions to rare genetic diseases better than other methods, you should consider this company if you’re willing to take a calculated risk with a company that may provide you with better health screening than some of the bigger names out there, like 23andMe. At the very least, keep it in mind if you’re looking for a lot of detail, because Helix definitely ticks that box.

Helix’s Health and Wellness Tests

These tests aim to help you identify your genetic risks for certain diseases or your carrier status for conditions you could pass on to your children. They can also help you identify wellness issues to do with things like sleep, caffeine consumption, and stress. Since these are considered to be genetic “traits,” some of them can be found in the Ancestry & Traits section of Helix’s website (rather than the Health section).

GenePrism: Actionable Insights

This test (by PerkinElmer Genomics) tells you if you’re at elevated genetic risk of disease, so that you can make more informed health decisions for you and your family. It features:

  • Tests for 32 inherited cancers, heart disease, and other health conditions
  • Actionable advice on disease prevention and early detection
  • Access to a genetic counselor at no additional cost

Mayo Clinic GeneGuideTM

This test can tell you how genetics can affect your health, disease risk, and carrier status. However, not everyone will qualify. You need to first submit a health questionnaire to be approved by a PWNHealth physician before your test is ordered. The report features:

  • Personalized insights and interactive tools
  • Four disease risk reports; four carrier status reports
  • Your response to certain medications (e.g., Ibuprofen metabolism)
  • The authority of the world-renowned Mayo Clinic
  • The ability to build a family tree, to document your relatives’ health history

CarrierCheck

This test assesses your carrier status for 67 inherited conditions, which is a lot more than most other companies’ carrier tests. This is great if you’re planning to start a family and want to be proactive about your child’s health. The report features:

  • Access to educational resources, to learn more about the tested conditions
  • Access to genetic counselors who can answer your questions

Heart Start

The test provides detailed insights into your genetic risk for cardiovascular disease, and it tells you what you can do about it. It features:

  • Blood-based lab testing as well as genetic analysis from your saliva sample
  • Measurements of total lipid amounts and fatty acids, plus markers of inflammation, to give a comprehensive look at your heart health
  • Telephone consultations and lab appointments to suit your schedule

Note that this test requires you to get your blood drawn as well as submitting a saliva sample.

Prostate Cancer Genetic Risk Score  

This test is intended to measure your lifetime risk of developing prostate cancer. Please note that only males of African American, East Asian, and Non-Hispanic White ethnic backgrounds are able to order this test. You’ll need to first submit a health questionnaire to determine if you are eligible. The test features:

  • Assessment of multiple genetic markers to calibrate your risk profile
  • Guidance on making more informed decisions about screening
  • Access to genetic counseling

See Helix Deals

Similar Test Kits Available

  • Living DNA offers individual tests and a combined wellbeing and ancestry kit, which looks into your nutritional and exercise profile, including a full vitamin report.
  • LetsGetChecked has tons of individual health tests on offer, looking at everything from hormone levels and thyroid management to STDs.
  • 23andMe assesses your genetic risk for 13 common diseases and your carrier status for 44 congenital conditions. Its test explores traits related to sleep, weight, muscle composition, and more, and it comes with a very detailed ancestry report.

Possibly Worth the Price for Exome Sequencing

Helix accepts payments via Visa, MasterCard, American Express, and most other credit cards.

Most of Helix’s DNA tests are more expensive than similar ones from other companies, which could be because of its exome sequencing approach (rather than the more usual genotyping).

However, Helix does offer three tests for free, if you are already a Helix customer. After an initial purchase, you can also access most other tests at a discounted rate (sometimes at just 10% of the list price)!

Exome sequencing can identify the genetic variants in all of an individual’s genes, including very rare genetic variants that are only present in a small number of individuals. If this means it can pick up the gene variants for a rare Mendelian disease, it may well be worth paying the high price – at least for the first test.

祖先血统
kit
Ancestry
  • 结果分为26个区域组
  • 找出您是否有特定的适应能力,包括海拔和极地气候
  • 您可进行单独测试以确认您的尼安德特人血统

Support Is Satisfactory If You Ask a Specific Question

Helix’s self-support resources are provided in the form of a searchable Help Center populated with articles arranged into various categories. The accompanying chatbot always appears to be offline, but maybe I’ve just been unlucky.

Helix Review

If the self-support resources don’t answer your questions, you can call the company or fill out the “Contact Customer Support” form. I submitted an initial question to ask about whether the reports were worth the cost, and the support agent responded with a somewhat generic answer.

I asked a second question about the availability of tests internationally. This time, I received a more targeted response:

Helix Review

See Helix Deals

Higher Prices for Better Insights (and Some Free Stuff)

One of Helix’s key selling points is its use of exome sequencing rather than genotyping, which means that – theoretically – it could discover predispositions to rare genetic diseases that other companies’ DNA tests don’t detect. I can’t be sure that it does, and since I’m unlikely to be one of those rare cases, I’d personally prefer to take my chances with one of the other testing companies that cost less.

It is true to say that Helix goes into greater detail than most of its competitors in certain areas. For example, its CarrierCheck tests your carrier status for 67 different conditions. Likewise, the GenePrism: Actionable Insights report includes genetic risks for 32 diseases.

If you do decide to make the purchase, remember that getting your genome sequenced via one of Helix’s expensive tests also entitles you to free additional reports for Ancestry and Wellness (including one specifically for Women’s Wellness). Be sure to put these in your cart for better value-for-money.

See Helix Deals

FAQs

How accurate is Helix?

Helix is adequate in terms of accuracy. However, it can’t yet compare to some of the bigger names on the market, e.g., 23andMe and Ancestry DNA, when in this area. That’s in part due to its database size, which is comparably much smaller.

How long does it take to receive results from a Helix test?

Approximately 1-2 months.

How does Helix compare to other DNA testing competitors?

Helix performs exome sequencing on your DNA sample. This is a technology that charts the entire protein-coding region of your genome. In theory, this type of sequencing should provide a more detailed and nuanced perspective on your DNA.

How much does a Helix test cost? (Any discounts?)

Most of Helix’s DNA products are on the more expensive side of the pricing spectrum than what you’d get from similar companies. That’s probably due to the testing methodology it uses (exome sequencing approach). On the bright side, however, Helix does offer three tests for free if you’re a customer already. After an initial purchase, you can also access most other tests at a discounted rate (sometimes at just 10% of the list price).

Who should consider taking a Helix test?

Given that Helix uses exome genome sequencing , which (in theory) can discover predispositions to rare genetic diseases better than other methods, you consider this company if you’re willing to take a calculated risk with a company that may provide you with better health screening than some of the bigger names out there, like 23andMe. At the very least, keep it in mind if you’re looking for a lot of detail, because Helix definitely ticks that box.

我们基于严格的测试和研究对服务提供商进行排名,同时也会考虑用户反馈以及我们与提供商之间签订的商业协议。本页面包含联盟链接。 Learn more.
莫斯·斯特恩
莫斯·斯特恩
撰稿人
莫斯·斯特恩是一位职业作家,业余爱好音乐、阅读、骑行,喜欢拼字游戏,潜心钻研健康和科学领域。目前居住在美国宾夕法尼亚州费城附近。

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